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Each day in the United States, nearly 1,300 youth under 18 years of age use smokeless tobacco for the first time, more than 950 of whom are male

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In February 2008, the FDA issued a statement which suggested that their evaluation indicates it is increasingly likely that there may be an association between Chantix and serious neuropsychiatric symptoms. In July 2009, the FDA required Pfizer to add a prominently displayed boxed warning about the risk of behavior changes, depression, hostility and suicidal thoughts, which is the strongest warning that can be placed on a prescription medication

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Rowland, 1990

The bodys addiction fades in a matter of weeks, but the habit loop takes much longer to kill