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Cochrane Database of Systematic Reviews, titled Nicotine receptor partial agonists for smoking cessation, indicates that Varenicline increases the likelihood of quitting smoking by about 60% compared to placebo

2018;360:j5855

Studies show that smokers of these products often inhale more deeply or smoke more cigarettes to achieve the same nicotine effect, maintaining exposure to similar levels of harmful chemicals

The BMC Public Health study also looked into heavier levels of alcohol consumption and estimated that drinking three bottles of wine per week (around 30 units) could increase lifetime cancer risk by 3.6 per cent in women and 1.9 per cent in men, or 36 in 1,000 women and 19 in 1,000 men