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There were no significant interactions seen between smoking and drinking for any of the causes of death (all cause p = 0.85, CHD p = 0.39, stroke p = 0.91, alcohol-related p = 0.47, respiratory p = 0.44 and smoking-related cancer p = 0.72)

The two substances in combination became very popular and were also smoked in normal "dry" pipes

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The study received institutional review board (IRB) approval from Kings College London Psychiatry, Nursing and Midwifery Research Ethics Subcommittee (PNM RESC)