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The meta-analysis of the risk of lower respiratory infections associated with SHS exposure included 50 studies 53,64,91,134,362,363,364,365,366,367,368,369,370,371,372,373,374,375,376,377,378,379,380,381,382,383,384,385,386,387,388,389,390,391,392,393,394,395,396,397,398,399,400,401,402,403,404,405,406,407 and 66 observations (Supplementary Table 9) and yielded an RR and uncertainty interval inclusive of between-study heterogeneity of 1.34 (0.812.19) (Table 2, Fig