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Of these, more than 7 million are due to direct tobacco use, while around 1.3 million non-smokers die from exposure to second-hand smoke

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Regular cigarette smokers were able to cover a longer distance in six minutes, while menthol smokers were more short of breath

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These findings indicate that the human metabolism of R -nicotine and its behavioral effects need to be investigated further, and that predictions about toxicological outcomes of R -nicotine consumption should not rely on animal model studies alone