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Given its low abundance and weak inhibitory activity (MAO-A: Ki = 52 M

There doesnt need to be a surfeit of empirical background, however

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Mortality for ex-smokers is shown in 4, which (bearing in mind the possible relevance of reverse causality) indicates that even a 60 year old cigarette smoker could gain at least three years of life expectancy by stopping (fig 4 (bottom graph))