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Drinking and smoking together amplify the risks associated with each substance, including increased chances of developing cancers, heart disease, stroke, and respiratory issues

The right response may be a dose change, timing change, more therapy support, or a different medication strategy

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48 Because the serum concentrations of nicotine achieved with the recommended dosages of NRT are generally much lower than those attained with smoking, most experts have concluded that the risks associated with NRT use in patients with cardiovascular disease are minimal relative to the risks of continued tobacco use

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