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JUUL took these marketing tactics offline by hosting lounges, exclusive events and parties with free tastings. Events also featured appearances by young influencers, cultivated through a JUUL launch influencer seeding program. JUUL also engaged celebrities by offering a VIP portal on its website for exclusive discounts, reserved access to limited edition colors and early access to future product launches. Similarly, PMI advertised its IQOS product at select international locations, including pop-up boutique stores in exclusive urban centers, to create the illusion of a high-end product

It is especially important that states do everything they can to push forward policies that protect their residents

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Heavy smokers defined by prediagnostic circulating cotinine levels had a multivariable-adjusted HR for death of 1.76 (95% CI, 1.23 to 2.51) compared with nonsmokers