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Because they are systemic, the chemicals are absorbed into the plants tissues including pollen and nectar exposing bees and other pollinators

The walls in a house are porous enough to absorb smoke, and painting over them (even using a high-quality sealer) wont be good enough unless you scrub them down

"Smaller crops in South America, Africa and the United States
Chemical exposure and health risks Studies suggest that heated tobacco products emit less harmful chemicals than traditional cigarettes, however, it's important to highlight that they still contain some toxic compounds [3]
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Justinova, Z., Le Foll, B., Redhi, G
