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GERD is the most common digestive disorder, occurring in up to 20% of Americans

The findings therefore may not be generalizable to the Chinese population living in underdeveloped rural areas or smaller cities

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The discrepancy in findings can create a significant problem when addressing regulatory or clinical questions posed by the expansion of e-cigarette use

Further research, including direct comparisons with non-smokers and more detailed toxicological assessment, is needed to clarify the reproductive risks of E-cigarettes and guide fertility counseling