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102 compared number processing performance and neural responses during the task in women taking OCs, men, and nonusers scanned once during the follicular phase and once during the luteal phase and found that women taking OCs performed similarly to NC women in their follicular phase, yet had similar neural activation patterns to men

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In 2010, the Food and Drug Administration (FDA) issued warning letters to manufacturers citing "violations of good manufacturing practices, making unsubstantiated drug claims, and using the devices as delivery mechanisms for active pharmaceutical ingredients." They also mentioned, however, that the effects of e-cigarettes are unclear, and included a phone number for people to report any adverse events