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Immediate effects loss of inhibition spontaneous laughter quiet and reflective mood affected perception including sound, colour and other sensations confusion altered thinking and memory anxiety mild paranoia altered vision reddened/bloodshot eyes relaxation sleepiness reduced coordination and balance increased heart rate low blood pressure increased appetite

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Estimated annual percentage change and percentage change (EAPC) The EAPC is a statistical indicator used to quantify the average annual change rate of health-related indicators in a specific time period, such as incidence rate, mortality, and disability-adjusted life years 22

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