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Long-term use tobacco products create nicotine dependence and quitting cold turkey can cause intense withdrawal symptoms such as increased urges, irritation, restlessness, difficulty concentrating, insomnia, increased appetite, anxiety, and depression among others

They had shot the pilot, and were finishing up a six-episode run when his buddy, who ran construction on the show, had to leave, leaving Cudlitz to finish the final episode

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While he might have realized the impact his protagonists would have on pop culture, television, and storytelling at large, Carter probably didnt anticipate that a character defined by his chain-smoking habit would become such a lasting figure, too

(2010) Using focus groups in community-based participatory research: challenges and resolutions

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