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Smokers who expect a cigarette-like smoky hit often find the first few sticks taste different before they adjust

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Clinical and pharmacologic factors that may influence these effects include: Individual genetics and metabolism, which affect how both cannabis and medications are processed Medication dosage and cannabis potency, including THC concentration, frequency of use, and method of consumption Due to these variables, mental health providers often recommend caution and close monitoring when cannabis is used alongside antidepressant medications

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Participants, investigators, and research staff will be blind to group A or B assignment

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