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First, the tobacco is cut into individual blocks, then into thin slices

These products are intended only for adult 21+ current nicotine users and are not for non-users

Visible signs such as premature aging and bad breath are also common

Summaries of Company Responses Alliance One International Alliance One International (AOI), headquartered in the United States, describes itself as a leading independent leaf tobacco merchant serving all of the major consumer tobacco product manufacturers through tobacco purchases in more than 35 countries.[285] AOI operates in Zimbabwe through its subsidiary Mashonaland Tobacco Company (MTC), which purchased 19.7 percent of the Zimbabwe tobacco crop in 2017

Nicotine and cotinine tests are designed to detect nicotine exposure

doi: 10.1172/JCI76304 67 MayerE