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References 1.Moran MB, Pierce JP, Weiger C, et al

In a sensitivity analysis excluding these individuals, we observed similar results for each of the biomarkers examined (total NNAL, NNN, and 1-Hop) to our results when including them

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Apoptosis assay Cells were cultured in 96-well plates (5000 cells/well) and 0.1% IncuCyte Caspase-3/7 Green Reagent (Essen Bioscience) was added to the medium with PG or Gly to detect caspase 3/7-activated cells