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After years of debate in the European Parliament, the 2014 Tobacco Products Directive banned flavored cigarettes in the EU as of May 2016, and menthols as of May 2020

If the BMD as preferred toxicological threshold for MOE assessment is unavailable, no observed effect levels (NOEL), no observed adverse effect levels (NOAEL) or lowest observed adverse effect levels (LOAEL) may be applied

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