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In addition, checkpoint proteins ATM, Chk1, and Cdc25 are phosphorylated and activated in zygotes fertilized with H 2 O 2 -treated sperm (Song et al., 2014), which indicates that embryos fertilized with treated sperm might be arrested at the G2/M checkpoint through the ATM Chk1 Cdc25B/Cdc25C pathway

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