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ROS cause oxidative stress, which damages cellular proliferation, metabolism, and health, and can be involved in the development of several cardiovascular (e.g., atherosclerosis), respiratory (e.g., chronic obstructive pulmonary disease, asthma), and neurodegenerative disorders (e.g., Parkinsons disease, multiple sclerosis) as well as diabetes, rheumatoid arthritis, and some types of cancers (e.g., lung, colorectal) (Domej et al., 2014

Acknowledgments AS is supported by the UNC Lineberger Cancer Control Education Program (R25 CA57726)

A recent bout of hospitalisations in the US led to an outbreak of public concern that e-cigarettes are not a safe alternative to smoking cigarettes

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