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In some cases, its very obvious

Effect of personal exposure to PM2.5 on Respiratory Health in a Mexican panel of patients with COPD

Alcohol is a depressant that slows down the brain and nervous system

Cribbed from here: They didn't indicate any specific N/S/E/W regional applications there though and present it as a more generalized thing, but maybe it's because the guy was an outsider hisself, he sed he'd heard those in the 70's when he moved to Notts, so who knows

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