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[PubMed: 12169572] Koike E, Hirano S, Shimojo N, Kobayashi T

But the bad news doesn't stop there

- passed away from lung cancer in 1999, aged 69

It can also cause discoloration of the nails, causing them to become yellowed or brown

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This extended presence makes cotinine the preferred marker for blood-based nicotine testing in clinical settings
