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The study concluded that heavy smokers (40+ cigarettes/day) had the softest night-time erections, and smoking was likewise related to an abnormal decline of blood pressure in the penis

[DOI] [PubMed] [Google Scholar] 87.Vansickel A.R., Eissenberg T

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The study also showed that although the heritability of lung function and COPD was estimated to be between 38 and 50%, individual genetic variants only account for a small fraction of the overall risk associated with COPD [50]