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Has the applicant demonstrated that the following statement in their proposed modified risk labeling and advertising is true: Scientific studies have shown that switching completely from cigarettes to the IQOS system significantly reduces your bodys exposure to harmful or potentially harmful chemicals.
The chemicals in cigarettes reduce blood flow to the skin, deplete essential nutrients, and break down collagen and elastin, resulting in premature wrinkles, sagging skin, and a dull complexion
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Lancet 2 , 754758 (1973)

23 June 2017.
