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Key red flags include pregnancy (no safety data, so contraindicated), active cancer (caution due to growth effects), autoimmune disorders, or organ failure

It means precision matters more outside controlled environments

doi: 10.1016/j.siny.2009.11.001

Stability of curcumin in oil-in-water emulsions: impact of emulsifier type and concentration on chemical degradation

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Risk factors for inflammation associated with autism include maternal (odds ratio [OR] = 1.6, confidence interval [CI] 95% = 1.12.2) and perhaps paternal (OR = 1.4, CI 95% = 1.02.0) autoimmune diseases such as diabetes, myasthenia gravis, idiopathic thrombocytopenic purpura, or rheumatic fever, 1 maternal obesity (OR = 1.67, CI 95% = 1.12.56), 2 and febrile episodes during the first two trimesters (OR = 1.6, CI 95% = 1.02.5)