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However, there are also risks and potential side effects, including: Temporary urine retention Urinary tract infection (UTI) Dry orgasm Incontinence Erectile dysfunction In some cases, additional treatment may be needed after TUIP

doi: 10.1038/ng0506-500 31 BolgerAMLohseMUsadelB

PIs should understand: what data goes to the DMC how frequently it is reviewed how decisions are documented and communicated how local site actions align with global oversight If your trial uses a DMC, study the structure here: DMC roles explained

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