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The same group also reported that MRP7 has a broad resistance profile for natural product agents, conferring high levels of resistance to docetaxel (46-fold), paclitaxel (116-fold), SN-38 (65-fold), daunorubicin (7.5-fold), etoposide (11-fold), and vincristine (56-fold)[167]
Modeling 19 , 132 (2013)
Therefore, it is essential to consider these factors in conjunction with size to develop liposomal formulations that maximize drug delivery and therapeutic outcomes in dermatology [32]
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doi: 10.1016/0006-291X(65)90316-5 30 HouD.JiaX.WangL.McGrathS
