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In patients with T2DM and other metabolic abnormalities, elevated SELENOP levels exacerbate IR and reduce the efficiency of insulin transport into the CNS, thereby compounding metabolic dysfunction and possibly contributing to neurodegenerative processes [224]

Additionally, the use of myelotoxic agents, including certain antibiotics and immunosuppressants, may compound bone marrow suppression and worsen clinical outcomes 9

doi: 10.3390/antibiotics14030242

Unfortunately, cohort studies conducted in 2012 did not confirm the role of polymorphisms in genes GSTM1 , GSTT1 , and GSTP1 in the development of AMD [108]

Querido, J
