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These compounds are associated in a set of reactions known as AsA-GSH cycle

Mental symptoms included insomnia, dizziness, anxiety, low mood, and cognitive decline, characterized by trouble concentrating, confusion, and memory problems

Considering that SGLT2 is primarily expressed in the kidneys, the mechanisms by which SGLT2 inhibitors reduce the cardiovascular risk and directly affect the atherosclerotic plaque, beyond glucose- and body weight-lowering effects, are not completely clear (338, 339)

Thus, the extensive chemical rearrangement justifies the spectrophotometric changes of hemin by thiols, and iron appears to be necessary for the completion of the reaction