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Vigorous agitation can shear and denature the molecules

These results support the idea that EAR-20 enhances receptor activity not only by promoting channel opening, but also by limiting desensitization, a dual mechanism likely contributing to its robust potentiation observed

Although most cases of glaucoma show elevated IOP values, there are patients with glaucomatous optic neuropathy whose pressure values are within the normal range (normotensive glaucoma), or who, despite elevated IOP values, do not present damage to the ON head (Jonas et al., 2014)

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J Exp Bot 53:13051319 Shigeoka S, Nakano Y, Kitaoka S (1980) Purification and some properties of L-ascorbic acid-specific peroxidase in Euglena gracillis