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Free Radic Biol Med 208:445457 Koppula P, Zhang Y, Zhuang L, Gan B (2018) Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer
Vitamin B12 injections (hydroxocobalamin in the UK) are prescribed for documented deficiency states such as pernicious anaemia and malabsorption disorders
Herman C
The utilisation of inhibitors of glutamine metabolism has been demonstrated to promote ROS formation and desensitization in PC cells, consequently resulting in altered cytokine-cytokine receptor interaction pathways, including those involving CCL5, CCR4, LTA, CXCR4, IL-6R and IL-7R, which in turn promote iron death [53]
The novel imipridone ONC212 induces pronounced anti-leukemia effects in vitro and in vivo and is highly synergistic with the BCL-2 inhibitor ABT-199
doi: 10.1007/s00404-012-2237-2 16 TeedeHJTayCTLavenJJEDokrasAMoranLJPiltonenTTet al
