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[2] Choline chloride serves as an essential substrate for phosphatidylcholine and betaine formation, thereby enhancing bile-dependent lipid emulsification and acting as an osmolyte that maintains hepatocyte membrane integrity under oxidative stress

Its a big change

While that is an opinion, it reflects a growing sentiment that doctors stepping outside the bounds of evidence-based medicine with peptides are leaving themselves exposed to lawsuits

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people with known cardiovascular disease, arrhythmia, or uncontrolled hypertension (chronic high-dose human data do not exist)