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Most clinical datasets lie between these extremes and exhibit mosaic pairing shaped by care pathways, including whether a biopsy is performed, whether spent media are retained, and whether cycles proceed to transfer [450, 451]

*Correspondence: Jianqun Lin [email protected] Pang [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process
