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Another target of protein Kla involved in the regulation of the sensitivity of tumor cells to therapy is methyltransferase-like 3 (METTL3), an enzyme responsible for RNA N6-methyladenosine (m 6 A) [103,104,105]

doi: 10.1161/CIRCULATIONAHA.118.039345 153

Thus, psychological stress may influence the development of depression by triggering abnormal lipid oxidation

Considering the emerging reports of suppressed AGXT and impaired glyoxylate/oxalate metabolism in MASLD 12,15,16,17 , and to address the mechanisms by which oxalate promotes MASH, we studied the effects of oxalate on molecular and metabolic drivers of MASH in hepatocytes