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doi: 10.1016/j.neuint.2019.02.008 234 WangHMWangLWLiuXMLiCLXuSPFarooqAD

The following sections will summarize a few examples of how amino acid metabolism influences T cell exhaustion (Figure 3)

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10.14336/AD.2023.0727 108 DesbonnetL.ClarkeG.TraplinA.O'SullivanO.CrispieF.MoloneyR

Notably, Asn82 of leptin lies in near the center of the site 2 interface and makes key hydrogen bonds contacts with LepR residues Ser505 and Leu503, suggesting a loss of site 2 binding associated with the N82K mutation (Fig