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Archived from the original on 19 May 2020
At the onset of motor symptoms, R6/1 mice displayed reduced striatal expression of PAC 1 R levels, which IN-PACAP restored, while it additionally restored levels of CREB-binding protein and BDNF [203]
Moreover, 8-oxo-2-deoxyguanosine RNA modifications caused by oxidative stress can serve as an additional factor causing decreased miR-107 levels (448)
Dysregulated features were identified using our data processing technology (XCMS) 16 combined with a database we developed (METLIN) 17,18
The invivo redox state of Mia40 at steady state is about 70% oxidized (Figure 7B)
