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10.1016/j.jep.2011.08.001 10 ChenC.WangY

This is critical data to have before seeking FDA approval

AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

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We found that cell viability was significantly restored by ferroptosis inhibitor ferrostatin-1 (Fer-1) treatment in ACTL6A-ablated cells but not by apoptosis inhibitor ZVAD-FMK or necroptosis inhibitor necrostatin-1 treatment (Fig