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Accordingly, inhibition of key glycolytic enzymes such as PKM2 and GAPDH, through oxPTMs (on Cys 358 and Cys 152 , respectively), can divert glucose away from glycolysis towards PPP for regeneration of redox equivalents which can be forwarded to enzymes such as GR to enable glutathione recycling 8,61 (Fig

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doi: 10.1016/j.jada.2004.05.213

Chaudhry IB, Husain N, ur Rahman R, Husain MO, Hamirani MM, Kazmi A et al (2015)