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3 Therapy-induced senescence Conventional approaches to cancer treatment, such as chemotherapy or radiotherapy, involve the use of cytostatic drugs or ionizing radiation to eradicate cancer cells [52]
Prostate cancer vasculature may express surface prohibitin in configurations similar to adipose vasculature, making it potentially vulnerable to the same targeting approach
Platinum neurotoxicity pharmacogenetics

Nat Commun 12 , 2002 (2021)

Notably, deletion of GPX4 caused severe phenotypic abnormalities in mice in animal experiments, whereas deletion of the ALOX12 gene did not cause major developmental defects in mice

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