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This condition is related to significant DNA damage and genomic instability, leading to neoplastic progression and initiation (Valavanidis et al., 2013)
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Similarly, proteins and small-molecule antioxidants such as glutathione (GSH) are vulnerable to ROS, leading to impaired cellular redox buffering, mitochondrial dysfunction, and diminished contractile and neuronal function [39]
Even a single temperature excursion above 8Csuch as leaving the vial on a countertop for several hourscan denature the peptide structure, turning an effective compound into an inactive solution
