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Erythrocytes were treated with OPFR for 24 h at concentrations ranging from 0.001 to 1,000 g/mL
However, its potential delayed toxicity related to cobalt accumulation in tissue remains unknown

A large RCT is needed to solidify the abovementioned findings

Too much MIC B12 dosage can lead to side effects, such as headaches or nausea, so its important to start with a lower MIC B12 dosage and gradually increase according to how your body responds

10.1089/ars.2013.5603 40

In summary, the changes in diet can alter the excretion of porphyrin-precursors in AHP patients
