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High-dose niacin therapy is normally contraindicated in individuals with active peptic ulcer disease or active liver disease

This is especially important for pernicious anemia patients or anyone suffering from high homocysteine levels

Healthy B12 levels can be sustained with monthly supplementation

B., Comas, I

B12 deficiency is sometimes associated with poor cognition, taking B12 reduced their cognitive problems - Feb 2021 Medical Journal Armed Forces India Background Vitamin B12 deficiency is an easily treatable cause of reversible dementia

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