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In this Review, the authors examine the contribution of abnormalities in the glutamatergic system to the impairments in neural plasticity that are observed in patients with mood disorders, and how this knowledge can be applied to the development of antidepressants with more rapid and sustained effects.

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this causes a decrease in the number of red blood cells which develops when the body lacks the intrinsic factor necessary to naturally absorb vitamin B-12 available in the foods that we eat
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