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H., Bozinovski S., Hertzog P
A major challenge in the clinical application of exosomes is stabilizing their secretion in vivo

NAD + and precursors supplementation NAD + can be directly supplemented intravenously to increase cellular NAD + levels, which has been observed in healthy and elderly cohorts, suggesting improvements in cognitive function and increased expression of antioxidant genes, although these trials were conducted in small cohorts 66,116,117

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The primers used for the construction of the above plasmids are (uppercase letters represent RE sequence): pJL6, Pvha-6 SphI F 5actGCATGCagcacagaactgcattaagtatac, vha-6 AgeI R 5actACCGGTCtaccagaaccaccgtgatcgagtccctcgtaaacg
