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Int J Alternat Med

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The paw withdrawal frequency assay sought to examine the rate of paw withdrawal responses to capsaicin over a hypothetical 24-hour period

It has been reported that H 2 S can relax rat aortic tissues in vitro in an ATP-sensitive K + (K ATP ) channel-dependent manner and that H 2 S at physiologically relevant concentrations induces vasorelaxation via activation of K ATP channels in isolated mesenteric artery smooth muscle cells (17, 84)