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doi: 10.1111/acel.v22.10 136 LeeYLeeSChangSCLeeJ

studied the effect of TMAO on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD model mice (Quan et al., 2023), determining 5-HT levels and its metabolites in the striatum via high-performance liquid chromatography to explore TMAOs effect on striatal neurotransmitters

Animal studies have demonstrated that type 1 diabetes mellitus (T1DM) can lead to testicular atrophy, disruption of seminiferous tubule architecture, and impaired spermatogenesis through multiple mechanisms, including oxidative stress, apoptosis, endocrine dysregulation, autoimmune responses, and epigenetic alterations [4, 5]

Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the international diabetes federation diabetes atlas, 9th edition