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Mice fed a high-iron diet and mice with mutations associated with hereditary hemochromatosis (an iron overload disease caused by inherited mutations in genes that regulate iron metabolism) both developed ferroptosis-related liver damage [33]

Biosynthesis and Synthesis of ALA 2.1

[DOI] [PMC free article] [PubMed] [Google Scholar] 404.Zaky, A., Glastras, S

Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease

CoA-LOT: BN20240511/CA

Another strategy is to adjust patients diets and lifestyles, such as adopting low-sugar diets or increasing physical activity, to positively affect metabolic health