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Description
Glutathione (GSH) is the most abundant L MW SH so we develop an orthogonal approach to quantify GSS , enabling corroboration of L MW SS measurements by sulfur atom trapping

The glucocorticoid dexamethasone inhibits HIF-1 stabilization and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages

J Pharmacol Exp Ther 298:197200
The assay is based on the conversion of citrate to isocitrate, to -ketoglutarate, which results in the production of NADPH

Hoskinson C, Dai DLY, Del Bel KL, Becker AB, Moraes TJ, Mandhane PJ, Finlay BB, Simons E, Kozyrskyj AL, Azad MB, Subbarao P, Petersen C, Turvey SE (2023) Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease

These findings do not establish safety, efficacy, or suitability for any human or animal application, and have not been evaluated by the FDA or any regulatory agency
