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However, identifying impaired vitamin B12 status in the earlier stages is more challenging, but can be enhanced by using one or more plasma biomarkers of B12 status
This can cause a range of symptoms: Fatigue Weakness Tingling in hands or feet Memory or mood changes A smooth or sore tongue Dizziness Shortness of breath Vitamin B12 is mainly found in animal-based foods
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Cell Tissue Res 377, 153159 (2019)
It is important to bear in mind that IGF-1 serum concentration is 100-fold greater than insulin, however when bound to IGFBPs its biological activity is modulated and in its free-unbound form presents different effects [99, 157]
Higher within normal appears safe and may provide margin against future decline
