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The activation of Nrf2 plays a critical role in enhancing mitochondrial biogenesis, a process essential for optimising cellular energy production during exercise [57]

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

Other research has shown that high-dose antioxidant supplementation may interfere with the cardiovascular benefits of exercise, could have negative effects on the bodys natural anti-cancer activities and may affect how the body balances levels of different chemicals and nutrients on its own

Furthermore, also epigenetic risks have been debated, mostly focusing on methylation and imprinting

Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1