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doi: 10.1139/cjpp-2015-0305

18 The 2014 Practice Guideline by the AASLD and the European Association for the Study of the Liver (EASL) recommended the use of rifaximin as an add-on therapy to lactulose for prevention of HE recurrence

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And a positive trial for treatment in humans used intravenous administration, which may result in different bioavailability

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